Autonomic Nervous System, Inflammation, and Diabetes: Mechanisms and Possible Interventions

Autonomic Nervous System, Inflammation, and Diabetes: Mechanisms and Possible Interventions

1Hypertension Unit, Heart Institute (InCor), University of São Paulo Medical School, Rua Eneas de Carvalho Aguiar 44, 05403-000 São Paulo, SP, Brazil 2Nephrology Division, Department of Medicine, Federal University of São Paulo, 740 Botucatu Street, 04023-900 São Paulo, SP, Brazil 3Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, 3640 Colonel Glenn...

O 30: Peripheral Nervous System Diseases and Inflammation

Inflammatory neuropathies may be due to infection (with a specific casual agent identified) including Lyme disease, HIV, Leprosy, Herpes Zoster, Hepatitis B & C. The other group of are Autoimmune or possibly infectious (but with no specific causal infectious agent identified) including sarcoidosis, Guillain-Barre syndrome/ acute inflammatory demyelinating polyneuropathy ( AIDP), chronic in...

O4: Central Nervous System Involvement in Rheumatoid Arthritis: Possible Role of Chronic Inflammation and TNF Blocker Therapy

Rheumatoid arthritis (RA) is a chronic disease, the etiology of which has yet to be clarified, which causes activation of proinflammatory pathways that bring about joint and systemic inflammation. In recent years, the pathophysiology of CNS involvement that can occur in RA has attracted a great deal of attention. Emphasis has focused on the possibility that CNS involvement occurs due to bl...

Diabetes mellitus and the peripheral nervous system: manifestations and mechanisms.

Diabetes targets the peripheral nervous system with several different patterns of damage and several mechanisms of disease. Diabetic polyneuropathy (DPN) is a common disorder involving a large proportion of diabetic patients, yet its pathophysiology is controversial. Mechanisms considered have included polyol flux, microangiopathy, oxidative stress, abnormal signaling from advanced glycation en...

Autonomic Nervous System